EBM Publications
We gratefully acknowledge the financial support by the German Research Foundation (DFG), project 460333672 CRC 1540 EBM.
Research Data and Supplementary Materials
Research data, software, and supplementary materials from CRC 1540 EBM are openly available via the
EBM Zenodo Community:
EBM Publications (2023–present)
Journal articles, conference papers, and other research outputs from CRC 1540 EBM.
2025
Investigation of Class Separability within Object Detection Models in Histopathology
In: IEEE Transactions on Medical Imaging (2025)
ISSN: 0278-0062
DOI: 10.1109/TMI.2025.3560134 , , , , :
The Role of Perineuronal Nets in Physiology and Disease: Insights from Recent Studies
In: Cells 14 (2025), S. 321
ISSN: 2073-4409
DOI: 10.3390/cells14050321 , , , , , , :
Human brain tissue with MOGHE carrying somatic SLC35A2 variants reveal aberrant protein expression and protein loss in the white matter
In: Acta Neuropathologica 149 (2025), Art.Nr.: 23
ISSN: 0001-6322
DOI: 10.1007/s00401-025-02858-7 , , , , , , , , , , , , , , :
Modulator of VRAC Current 1 Is a Potential Target Antigen in Multiple Sclerosis
In: Neurology, Neuroimmunology and Neuroinflammation 12 (2025)
ISSN: 2332-7812
DOI: 10.1212/NXI.0000000000200374 , , , , , , , , , , , , , , , , :
A novel human organoid model system reveals requirement of TCF4 for oligodendroglial differentiation
In: Life Science Alliance 8 (2025), Art.Nr.: e202403102
ISSN: 2575-1077
DOI: 10.26508/lsa.202403102 , , , , , , , , , , , , , , :
Re-identification from histopathology images
In: Medical Image Analysis 99 (2025), Art.Nr.: 103335
ISSN: 1361-8415
DOI: 10.1016/j.media.2024.103335 , , , , :
Is Self-supervision Enough?: Benchmarking Foundation Models Against End-to-end Training for Mitotic Figure Classification
German Conference on Medical Image Computing, 2025 (Regensburg, 9. März 2025 - 11. März 2025)
In: Christoph Palm, Katharina Breininger, Thomas Deserno, Heinz Handels, Andreas Maier, Klaus H. Maier-Hein, Thomas M. Tolxdorff (Hrsg.): Informatik aktuell 2025
DOI: 10.1007/978-3-658-47422-5_15 , , , , , , :
MRI-based morphometric structural changes correlate with histopathology in experimental autoimmune encephalomyelitis
In: Journal of the Neurological Sciences 468 (2025), S. 123358
ISSN: 0022-510X
DOI: 10.1016/j.jns.2024.123358 , , , , , , , :
Printable ADA-GEL-based composite inks containing Zn-doped bioactive inorganic fillers for skeletal muscle biofabrication
In: Biomaterials Advances 172 (2025), Art.Nr.: 214233
ISSN: 2772-9508
DOI: 10.1016/j.bioadv.2025.214233 , , , , , , , :
Mechanical characteristics of spinal cord tissue by indentation
In: Journal of the Mechanical Behavior of Biomedical Materials 163 (2025), Art.Nr.: 106863
ISSN: 1751-6161
DOI: 10.1016/j.jmbbm.2024.106863 , , , , :
Do human brain white matter and brain stem structures show direction-dependent mechanical behavior?
In: Acta Biomaterialia (2025)
ISSN: 1742-7061
DOI: 10.1016/j.actbio.2025.04.004 , , , , , :
Mechanical characterization of a brain phantom material by combining experiments in the time and frequency domain
In: Journal of the Mechanical Behavior of Biomedical Materials 170 (2025), Art.Nr.: 107114
ISSN: 1751-6161
DOI: 10.1016/j.jmbbm.2025.107114 , :
Style-Extracting Diffusion Models for Semi-supervised Histopathology Segmentation
18th European Conference on Computer Vision, ECCV 2024 (Milan, 29. September 2024 - 4. Oktober 2024)
In: Aleš Leonardis, Elisa Ricci, Stefan Roth, Olga Russakovsky, Torsten Sattler, Gül Varol (Hrsg.): Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) 2025
DOI: 10.1007/978-3-031-73226-3_14 , , , , , , , , , , , :
2024
Tailored Bisacylphosphane Oxides for Precise Induction of Oxidative Stress-Mediated Cell Death in Biological Systems
In: ACS Chemical Biology (2024)
ISSN: 1554-8929
DOI: 10.1021/acschembio.4c00399 , , , , , , , :
Domain generalization across tumor types, laboratories, and species — Insights from the 2022 edition of the Mitosis Domain Generalization Challenge
In: Medical Image Analysis 94 (2024), Art.Nr.: 103155
ISSN: 1361-8415
DOI: 10.1016/j.media.2024.103155 , , , , , , , , , , , , , , , , , , , , , , , , , , , , , :
The Networking Brain: How Extracellular Matrix, Cellular Networks, and Vasculature Shape the In Vivo Mechanical Properties of the Brain
In: Advanced Science 11 (2024), Art.Nr.: 2402338
ISSN: 2198-3844
DOI: 10.1002/advs.202402338 , , , , :
Analysis of 1386 epileptogenic brain lesions reveals association with DYRK1A and EGFR
In: Nature Communications 15 (2024), Art.Nr.: 10429
ISSN: 2041-1723
DOI: 10.1038/s41467-024-54911-w , , , , , , , , , , , , , , , , , , , , , , :
On the relationship between viscoelasticity and water diffusion in soft biological tissues
In: Acta Biomaterialia 182 (2024), S. 42-53
ISSN: 1742-7061
DOI: 10.1016/j.actbio.2024.05.007 , , , , , , , , , , , , , :
Dynamic traction force measurements of migrating immune cells in 3D biopolymer matrices
In: Nature Physics 20 (2024), S. 1816-1823
ISSN: 1745-2473
DOI: 10.1038/s41567-024-02632-8 , , , , , , , , , , , , , :
Transport in cellular aggregates described by fluctuating hydrodynamics
In: Physical Review Research 6 (2024), Art.Nr.: 043064
ISSN: 2643-1564
DOI: 10.1103/PhysRevResearch.6.043064 , :
Comprehensive 7 T CEST: A clinical MRI protocol covering multiple exchange rate regimes
In: NMR in Biomedicine (2024)
ISSN: 0952-3480
DOI: 10.1002/nbm.5096 , , , , , , , , , :
Abstract
In: Epilepsia 65 (2024), S. 1-508
ISSN: 0013-9580
DOI: 10.1111/epi.18151 , , :
Abstract
In: Epilepsia 65 (2024), S. 1-508
ISSN: 0013-9580
DOI: 10.1111/epi.18151 , , :
Mean zero artificial diffusion for stable finite element approximation of convection in cellular aggregate formation
In: Computer Methods in Applied Mechanics and Engineering 419 (2024), S. 116649
ISSN: 0045-7825
DOI: 10.1016/j.cma.2023.116649 , , , :
Tensed axons are on fire
In: Proceedings of the National Academy of Sciences of the United States of America 121 (2024), S. e2321811121
ISSN: 0027-8424
DOI: 10.1073/pnas.2321811121 :
Information mismatch in PHH3-assisted mitosis annotation leads to interpretation shifts in H&E slide analysis
In: Scientific Reports 14 (2024), Art.Nr.: 26273
ISSN: 2045-2322
DOI: 10.1038/s41598-024-77244-6 , , , , , , , , , , , , , , , , , , , , , , , :
Model-driven exploration of poro-viscoelasticity in human brain tissue: be careful with the parameters!
In: Interface Focus 14 (2024)
ISSN: 2042-8901
DOI: 10.1098/rsfs.2024.0026 , , , , , , , , :
Beyond comparison: Brillouin microscopy and AFM-based indentation reveal divergent insights into the mechanical profile of the murine retina
In: JPhys Photonics 6 (2024), Art.Nr.: 035020
ISSN: 2515-7647
DOI: 10.1088/2515-7647/ad5ae3 , , , , , , , , , :
Identifying composition-mechanics relations in human brain tissue based on neural-network-enhanced inverse parameter identification
In: Mathematics and Mechanics of Solids (2024)
ISSN: 1081-2865
DOI: 10.1177/10812865231206544 , , , , , , :
Using dropout based active learning and surrogate models in the inverse viscoelastic parameter identification of human brain tissue
In: Frontiers in Physiology 15 (2024), Art.Nr.: 1321298
ISSN: 1664-042X
DOI: 10.3389/fphys.2024.1321298 , , , :
Rapid Stiffness Mapping in Soft Biologic Tissues With Micrometer Resolution Using Optical Multifrequency Time‐Harmonic Elastography
In: Advanced Science (2024)
ISSN: 2198-3844
DOI: 10.1002/advs.202410473 , , , , , , , , , , , , , , :
Nonlinear dynamics of femtosecond laser interaction with the central nervous system in zebrafish
In: Communications Physics 7 (2024), Art.Nr.: 161
ISSN: 2399-3650
DOI: 10.1038/s42005-024-01653-2 , , , , , , , , :
ILAE neuroimaging task force highlight: Subcortical laminar heterotopia
In: Epileptic Disorders (2024)
ISSN: 1294-9361
DOI: 10.1002/epd2.20206 , , , , , , , , , , , , , , , :
Multimodal assessment of brain stiffness variation in healthy subjects using magnetic resonance elastography and ultrasound time-harmonic elastography
In: Scientific Reports 14 (2024), Art.Nr.: 28580
ISSN: 2045-2322
DOI: 10.1038/s41598-024-79991-y , , , , , :
MEG in MRI-Negative Patients with Focal Epilepsy
In: Journal of Clinical Medicine 13 (2024), Art.Nr.: 5746
ISSN: 2077-0383
DOI: 10.3390/jcm13195746 , , , , , , :
Enzymatic Insitu Crosslinking Can Improve Hydrogel Stability While Maintaining Matrix Stiffness
In: ChemistrySelect 9 (2024), Art.Nr.: e202401700
ISSN: 2365-6549
DOI: 10.1002/slct.202401700 , :
Age-dependent increase of perineuronal nets in the human hippocampus and precocious aging in epilepsy
In: Epilepsia Open 9 (2024), S. 1372-1381
ISSN: 2470-9239
DOI: 10.1002/epi4.12963 , , , , , , , , , , , , , :
Time-harmonic optical flow with applications in elastography
In: Inverse Problems 40 (2024), S. 125026
ISSN: 0266-5611
DOI: 10.1088/1361-6420/ad9776 , , , , , :
Magnetic resonance elastography in a nutshell: Tomographic imaging of soft tissue viscoelasticity for detecting and staging disease with a focus on inflammation
In: Progress in Nuclear Magnetic Resonance Spectroscopy 144-145 (2024), S. 1-14
ISSN: 0079-6565
DOI: 10.1016/j.pnmrs.2024.05.002 , , , , , , , , :
Estimation of the mass density of biological matter from refractive index measurements
In: Biophysical Reports (2024), S. 100156
ISSN: 2667-0747
DOI: 10.1016/j.bpr.2024.100156 , , , , , , , , :
Cortical matrix remodeling as a hallmark of relapsing–remitting neuroinflammation in MR elastography and quantitative MRI
In: Acta Neuropathologica 147 (2024), Art.Nr.: 8
ISSN: 0001-6322
DOI: 10.1007/s00401-023-02658-x , , , , , , , , , , , , , , , :
A deep‐learning‐based histopathology classifier for focal cortical dysplasia (FCD) unravels a complex scenario of comorbid FCD subtypes
In: Epilepsia (2024)
ISSN: 0013-9580
DOI: 10.1111/epi.18161 , :
Appearance-based Debiasing of Deep Learning Models in Medical Imaging
German Conference on Medical Image Computing, BVM 2024 (Erlangen, 10. März 2024 - 12. März 2024)
In: Andreas Maier, Thomas M. Deserno, Heinz Handels, Klaus Maier-Hein, Christoph Palm, Thomas Tolxdorff (Hrsg.): Bildverarbeitung für die Medizin 2024. BVM 2024, Wiesbaden: 2024
DOI: 10.1007/978-3-658-44037-4_9 , , , , :
2023
A comprehensive multi-domain dataset for mitotic figure detection
In: Scientific Data 10 (2023), Art.Nr.: 484
ISSN: 2052-4463
DOI: 10.1038/s41597-023-02327-4 , , , , , , , , , , , :
Mechanical behavior of the hippocampus and corpus callosum: An attempt to reconcile ex vivo with in vivo and micro with macro properties
In: Journal of the Mechanical Behavior of Biomedical Materials 138 (2023), Art.Nr.: 105613
ISSN: 1751-6161
DOI: 10.1016/j.jmbbm.2022.105613 , , , , , , , , , , , , , :
A versatile implicit computational framework for continuum-kinematics-inspired peridynamics
In: Computational Mechanics (2023)
ISSN: 0178-7675
DOI: 10.1007/s00466-023-02415-7 , , :
Automated discovery of interpretable hyperelastic material models for human brain tissue with EUCLID
In: Journal of the Mechanics and Physics of Solids 180 (2023), Art.Nr.: 105404
ISSN: 0022-5096
DOI: 10.1016/j.jmps.2023.105404 , , , , , , , :
Inverse identification of region-specific hyperelastic material parameters for human brain tissue
In: Biomechanics and Modeling in Mechanobiology (2023)
ISSN: 1617-7959
DOI: 10.1007/s10237-023-01739-w , , , , , :
Ganglioglioma with adverse clinical outcome and atypical histopathological features were defined by alterations in PTPN11/KRAS/NF1 and other RAS-/MAP-Kinase pathway genes
In: Acta Neuropathologica (2023)
ISSN: 0001-6322
DOI: 10.1007/s00401-023-02561-5 , , , , , , , , , , , , , , , , , , , , :
Deep histopathology genotype–phenotype analysis of focal cortical dysplasia type II differentiates between the GATOR1-altered autophagocytic subtype IIa and MTOR-altered migration deficient subtype IIb
In: Acta Neuropathologica Communications 11 (2023), Art.Nr.: 179
ISSN: 2051-5960
DOI: 10.1186/s40478-023-01675-x , , , , , , , , , , , , , , , , , , , , , , :
Small leucine-rich proteoglycans inhibit CNS regeneration by modifying the structural and mechanical properties of the lesion environment
In: Nature Communications 14 (2023), Art.Nr.: 6814
ISSN: 2041-1723
DOI: 10.1038/s41467-023-42339-7 , , , , , , , , , , , , , , , , , , , , , , , , , , :
3T vs. 7T fMRI: capturing early human memory consolidation after motor task utilizing the observed higher functional specificity of 7T
In: Frontiers in Neuroscience 17 (2023)
ISSN: 1662-4548
DOI: 10.3389/fnins.2023.1215400 , , , , , , , , :
Tinten für die Biofabrikation–Druckbarkeit vs. Biokompatibilität?
In: BioSpektrum 29 (2023), S. 736-739
ISSN: 0947-0867
DOI: 10.1007/s12268-023-2046-0 , , , :
Mechanics in the nervous system: From development to disease
In: Neuron (2023)
ISSN: 0896-6273
DOI: 10.1016/j.neuron.2023.10.005 , :
A unifying finite strain modeling framework for anisotropic mixed-mode fracture in soft materials
In: Computational Mechanics (2023)
ISSN: 0178-7675
DOI: 10.1007/s00466-023-02359-y , , :
Mechanisms of mechanical load transfer through brain tissue
In: Scientific Reports 13 (2023), Art.Nr.: 8703
ISSN: 2045-2322
DOI: 10.1038/s41598-023-35768-3 , , :
Modeling the finite viscoelasticity of human brain tissue based on microstructural information
In: Proceedings in Applied Mathematics and Mechanics (2023)
ISSN: 1617-7061
DOI: 10.1002/pamm.202300234 , , , , :
Sox9 regulates melanocytic fate decision of adult hair follicle stem cells
In: iScience 26 (2023), Art.Nr.: 106919
ISSN: 2589-0042
DOI: 10.1016/j.isci.2023.106919 , , , , , , :
Brain tissue mechanics is governed by microscale relations of the tissue constituents
In: Biomaterials 301 (2023), Art.Nr.: 122273
ISSN: 0142-9612
DOI: 10.1016/j.biomaterials.2023.122273 , , , :
The specific DNA methylation landscape in focal cortical dysplasia ILAE type 3D
In: Acta Neuropathologica Communications 11 (2023), Art.Nr.: 129
ISSN: 2051-5960
DOI: 10.1186/s40478-023-01618-6 , , , , , , , , , , , :
Exploring the role of the outer subventricular zone during cortical folding through a physics-based model
In: eLife 12 (2023)
ISSN: 2050-084X
DOI: 10.7554/eLife.82925 , , :
Multifield computational model for human brain development: Explicit numerical stabilization
In: Proceedings in Applied Mathematics and Mechanics (2023)
ISSN: 1617-7061
DOI: 10.1002/pamm.202300288 , , :
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