Exploring Brain Mechanics
The central nervous system (CNS) is our most complex organ system. Despite tremendous progress in our understanding of the biochemical, electrical, and genetic regulation of CNS functioning and malfunctioning, many fundamental processes and diseases are still not fully understood. Only recently, groups of several PLs in this consortium, and a few other groups worldwide, have discovered an important contribution of mechanical signals to regulating CNS cell function. The CRC 1540 ‘Exploring Brain Mechanics’ will synergise the expertise of engineers, physicists, biologists, medical researchers, and clinicians in Erlangen and Berlin to exploit mechanics-based approaches to advance our understanding of CNS function and, as a long-term vision, to provide the foundation for future improvement of diagnosis and treatment of neurological disorders.
Join an engineer on a fascinating journey through the intricate world of neuroanatomy. At the first EBM harmonization workshop led by Prof. Dr. Friedrich Paulsen, participants gained a deeper understanding of the brain's anatomy through a brief seminar and an assisted brain dissection.
The team of X03 Boccaccini (DR: Markus Lorke and Sonja Kuth) visited the team of C02 Frischknecht (DR: Bartomeu Perelló Amorós) on 31.03.23 at the animal physiology labs for a lab shadowing and discussion of the planned experiments in the scope of the CRC EBM. Planned experiments will investigate th...
On 4 April 2023, project B01 (Oskar Neumann, PI: S. Budday) and Emmy-Noether research group BRAINIACS (Nina Reiter, PI: S. Budday) conducted some preliminary experiments on pig spinal cords. The main goal was to gain a feel for producing spinal cord samples and to become familiar with the experimen...
On 21 March 2023, project X03 (Markus Lorke and Sonja Kuth, PI: A.R. Boccaccini) and project C04 (Shanice Heidenreich, PI: A. Boßerhoff) performed their first collaborative experiments. The aim of this collaborative lab work was to familiarise ourselves with the different set-ups of experimental wor...
On March 17th, 2023, the Collaborative Research Center (CRC) 1540 "Exploring Brain Mechanics (EBM)" held its kick-off meeting at the Fraunhofer Institute for Integrated Systems and Device Technology (IISB) in Erlangen. The meeting started with EBM spokespersons' presentations on research areas and center structure. Then, Friedrich Paulsen presented the integrated graduate program and its qualification events.
